Latest posts
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Unlocking New Strategies to Combat Pancreatic Cancer
Understanding Pancreatic Cancer and Its Challenges Pancreatic adenocarcinoma (PDAC) is one of the most aggressive types of cancer, characterized by a dense stroma that composes nearly 80% of the tumor mass. This stroma, primarily organized by cancer-associated fibroblasts (CAFs), significantly influences tumor progression, immune suppression, drug resistance, and metastasis. Understanding this complex environment is crucial…
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Innovative Strategies to Target Cancer-Associated Fibroblasts in Pancreatic Cancer
The Role of Cancer-Associated Fibroblasts Pancreatic adenocarcinoma (PDAC) stands out as one of the most aggressive forms of cancer, characterized by a complex stroma that comprises nearly 80% of the tumor mass. A significant contributor to this dense stroma is the presence of cancer-associated fibroblasts (CAFs). These specialized cells not only support tumor growth but…